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SYT1 Antibody

Product Specifications

Background

The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca (2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin-1 participates in triggering neurotransmitter release at the synapse (Fernandez-Chacon et al., 2001 [PubMed 11242035]) .

NCBI Gene ID

6857

Swiss Prot

P21579

Accession Number

P21579

Host

Rabbit

Reactivity

Human

Immunogen

This SYT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 349-377 amino acids from the C-terminal region of human SYT1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Monkey, Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=57-214

Calculated Molecular Weight

48 kDa

Fragment

Rabbit Ig

Symbol

SYT1

NCBI Official Name

Synaptotagmin-1

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 02

Musch, M.W., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 298 (2), G203-G211 (2010) :

Background Reference 03

Kathir, K.M., et al. Biochim. Biophys. Acta 1798 (2) :297-302 (2010)

Background Reference 04

Pattaro, C., et al. BMC Med. Genet. 11, 41 (2010) :

Other Product Names

Synaptotagmin-1, Synaptotagmin I, SytI, p65, SYT1, SVP65, SYT

Tested Applications

WB, IHC-P

Protein ID

135086

Physical Properties

Liquid

Curated Selection

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