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ICAM3 Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule.

NCBI Gene ID

3385

Swiss Prot

P32942

Accession Number

P32942

Host

Rabbit

Reactivity

Human

Immunogen

This ICAM3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 282-310 amino acids from the Central region of human ICAM3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

60 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ICAM3

NCBI Official Name

Intercellular adhesion molecule 3

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 02

Han, S., et al. Hum. Immunol. 71 (7) :727-730 (2010)

Background Reference 03

Mosbruger, T.L., et al. J. Infect. Dis. 201 (9) :1371-1380 (2010)

Background Reference 04

Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19 (5) :1356-1361 (2010)

Other Product Names

Intercellular adhesion molecule 3, ICAM-3, CDw50, ICAM-R, CD50, ICAM3

Tested Applications

WB

Protein ID

206729872

Physical Properties

Liquid

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