Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

MMP2 Antibody

Product Specifications

Background

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

4313

Swiss Prot

P08253

Accession Number

P08253

Host

Rabbit

Reactivity

Human

Immunogen

This MMP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 303-331 amino acids from the Central region of human MMP2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Obesity

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat, Rabbit, Chicken

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=57-205

Calculated Molecular Weight

74 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

MMP2

NCBI Official Name

72 kDa type IV collagenase

NCBI Organism

Homo sapiens

Background Reference 01

Beshir, A.B., et al. Cancer Lett. 299 (2) :137-149 (2010)

Background Reference 02

Alakus, H., et al. WorldSurg 34 (12) :2853-2859 (2010)

Background Reference 03

Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :

Background Reference 04

Nikopensius, T., et al. Birth Defects Res. PartClin. Mol. Teratol. 88 (9) :748-756 (2010)

Other Product Names

72 kDa type IV collagenase, 72 kDa gelatinase, Gelatinase A, Matrix metalloproteinase-2, MMP-2, TBE-1, PEX, MMP2, CLG4A

Tested Applications

WB

Protein ID

116856

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Goat Amyloid beta peptide (Abeta) ELISA Kit
MBS263744-01 48 Well

Goat Amyloid beta peptide (Abeta) ELISA Kit

Ask
View Details
Goat Amyloid beta peptide (Abeta) ELISA Kit
MBS263744-02 96 Well

Goat Amyloid beta peptide (Abeta) ELISA Kit

Ask
View Details
Goat Amyloid beta peptide (Abeta) ELISA Kit
MBS263744-03 5x 96 Well

Goat Amyloid beta peptide (Abeta) ELISA Kit

Ask
View Details
Goat Amyloid beta peptide (Abeta) ELISA Kit
MBS263744-04 10x 96 Well

Goat Amyloid beta peptide (Abeta) ELISA Kit

Ask
View Details
Rat Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit
MBS2704670-01 24 Strip Well

Rat Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit

Ask
View Details
Rat Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit
MBS2704670-02 48 Well

Rat Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit

Ask
View Details