NKD1 Antibody

Product Specifications

Background

In the mouse, Nkd is a Dishevelled (see DVL1; MIM 601365) -binding protein that functions as a negative regulator of the Wnt (see WNT1; MIM 164820) -beta-catenin (see MIM 116806) -Tcf (see MIM 602272) signaling pathway.

NCBI Gene ID

85407

Swiss Prot

Q969G9

Accession Number

Q969G9

Host

Rabbit

Reactivity

Mouse

Immunogen

This NKD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 83-111 amino acids from the N-terminal region of human NKD1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

52 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

NKD1

NCBI Official Name

Protein naked cuticle homolog 1

NCBI Organism

Homo sapiens

Background Reference 01

Guo, J., et al. PLoS ONE (11), E7982 (2009) Creyghton, M.P., et al. Proc. Natl. Acad. Sci. U.S.A. 103 (14) :5397-5402 (2006) Creyghton, M.P., et al. Genes Dev. 19 (3) :376-386 (2005) Yan, D., et al. Proc. Natl. Acad. Sci. U.S.A. 98 (26) :14973-14978 (2001) Katoh, M. Int. J. Oncol. 19 (5) :963-969 (2001)