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TIAM2 Antibody

Product Specifications

Background

This gene encodes a guanine nucleotide exchange factor. A highly similar mouse protein specifically activates ras-related C3 botulinum substrate 1, converting this Rho-like guanosine triphosphatase (GTPase) from a guanosine diphosphate-bound inactive state to a guanosine triphosphate-bound active state. The encoded protein may play a role in neural cell development. Alternatively spliced transcript variants encoding different isoforms have been described.

NCBI Gene ID

26230

Swiss Prot

Q8IVF5

Accession Number

Q8IVF5

Host

Rabbit

Reactivity

Mouse

Immunogen

This TIAM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 357-385 amino acids from the N-terminal region of human TIAM2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

190 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

TIAM2

NCBI Official Name

T-lymphoma invasion and metastasis-inducing protein 2

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 02

Rabizadeh, S., et al. Cytokine Growth Factor Rev. 14 (3-4), 225-239 (2003) :

Background Reference 03

Salehi, A.H., et al. J. Biol. Chem. 277 (50) :48043-48050 (2002)

Background Reference 04

Yoshizawa, M., et al. Mech. Dev. 113 (1) :65-68 (2002)

Other Product Names

T-lymphoma invasion and metastasis-inducing protein 2, TIAM-2, SIF and TIAM1-like exchange factor, TIAM2, KIAA2016, STEF

Tested Applications

WB

Protein ID

296453025

Physical Properties

Liquid

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