PLXNC1 Antibody

Product Specifications

Background

PLXNC1 is a receptor for vaccinia virus semaphorin A39R and for herpesvirus Sema protein. Binding of viral semaphorins triggers cellular responses leading to the rearrangement of the cytoskeleton and to secretion of IL6 and IL8 (By similarity) .

NCBI Gene ID

10154

Swiss Prot

O60486

Accession Number

O60486

Host

Rabbit

Reactivity

Mouse

Immunogen

This PLXNC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1025-1054 amino acids from the C-terminal region of human PLXNC1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

176 kDa

Fragment

Rabbit Ig

Symbol

PLXNC1

NCBI Official Name

Plexin-C1

NCBI Organism

Homo sapiens

Background Reference 01

Liu, H., et al. Cell 142 (5) :749-761 (2010)

Background Reference 02

Lazova, R., et al. AmDermatopathol 31 (2) :177-181 (2009)

Background Reference 03

Scott, G.A., et al. J. Invest. Dermatol. 129 (4) :954-963 (2009)

Background Reference 04

Scott, G.A., et al. J. Invest. Dermatol. 128 (1) :151-161 (2008)

Other Product Names

Plexin-C1, Virus-encoded semaphorin protein receptor, CD232, PLXNC1, VESPR

Tested Applications

WB, IHC-P

Physical Properties

Liquid

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