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DHX32 Antibody

Product Specifications

Background

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The function of this member has not been determined. Alternative splicing of this gene generates 2 transcript variants, but the full length nature of one of the variants has not been defined.

NCBI Gene ID

55760

Swiss Prot

Q7L7V1

Accession Number

Q7L7V1

Host

Rabbit

Reactivity

Mouse

Immunogen

This DHX32 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 342-371 amino acids from the Central region of human DHX32.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

84 kDa

Fragment

Rabbit Ig

Symbol

DHX32

NCBI Official Name

Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32

NCBI Organism

Homo sapiens

Background Reference 01

Huang, C., et al. J. Exp. Clin. Cancer Res. 28, 11 (2009) :

Background Reference 02

Chen, Y., et al. Exp. Mol. Pathol. 82 (3) :256-261 (2007)

Background Reference 03

Alli, Z., et al. Anticancer Res. 27 (1A), 373-377 (2007) :

Background Reference 04

Alli, Z., et al. Exp. Mol. Pathol. 81 (3) :245-248 (2006)

Other Product Names

Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32, DEAD/H box 32, DEAD/H helicase-like protein 1, DHLP1, DEAH box protein 32, HuDDX32, DHX32, DDX32

Tested Applications

WB, IHC-P

Protein ID

74759011

Physical Properties

Liquid

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