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TMEM49 Antibody

Product Specifications

Background

Stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death. May be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis (By similarity) .

NCBI Gene ID

81671

Swiss Prot

Q96GC9

Accession Number

Q96GC9

Host

Rabbit

Reactivity

Human

Immunogen

This TMEM49 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 377-406 amino acids from the C-terminal region of human TMEM49.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Obesity

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

46 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

VMP1

NCBI Official Name

Vacuole membrane protein 1

NCBI Organism

Homo sapiens

Background Reference 01

Pardo, R., et al. Pancreatology 10 (1) :19-26 (2010)

Background Reference 02

Calvo-Garrido, J., et al. Mol. Biol. Cell 19 (8) :3442-3453 (2008)

Background Reference 03

Fujita, S., et al. J. Mol. Biol. 378 (3) :492-504 (2008)

Background Reference 04

Sauermann, M., et al. Oncogene 27 (9) :1320-1326 (2008)

Other Product Names

Vacuole membrane protein 1, Transmembrane protein 49, VMP1, TDC1, TMEM49

Tested Applications

WB

Protein ID

74731809

Physical Properties

Liquid

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