BTN3A1 Antibody
Product Specifications
Background
The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC) -associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A1; MIM 613590) and BTN3 (e.g., BNT3A1) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010 [PubMed 20208008]) .[supplied by OMIM].
NCBI Gene ID
11119
Swiss Prot
O00481
Accession Number
O00481
Host
Rabbit
Reactivity
Human
Immunogen
This BTN3A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 345-374 amino acids from the C-terminal region of human BTN3A1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
58 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
BTN3A1
NCBI Official Name
Butyrophilin subfamily 3 member A1
NCBI Organism
Homo sapiens
Background Reference 01
Smith, I.A., et al. J. Immunol. 184 (7) :3514-3525 (2010)
Background Reference 02
Shi, J., et al. Nature 460 (7256) :753-757 (2009)
Background Reference 03
Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345 (3) :1022-1032 (2006)
Background Reference 04
Mungall, A.J., et al. Nature 425 (6960) :805-811 (2003)
Other Product Names
Butyrophilin subfamily 3 member A1, CD277, BTN3A1, BTF5
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15126110 1 Vial
Lentiviral human COX18 shRNA (UAS) - Lentiviral human COX18 shRNA (UAS, iRFP) (25)
Ask
View Details 