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TBCC Antibody

Product Specifications

Background

Cofactor C is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state.

NCBI Gene ID

6903

Swiss Prot

Q15814

Accession Number

Q15814

Host

Rabbit

Reactivity

Mouse

Immunogen

This TBCC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-49 amino acids from the N-terminal region of human TBCC.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=57-065

Calculated Molecular Weight

39 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

TBCC

NCBI Official Name

Tubulin-specific chaperone C

NCBI Organism

Homo sapiens

Background Reference 01

Hage-Sleiman, R., et al. BMC Cancer 10, 135 (2010) :

Background Reference 02

Nature 447 (7145) :661-678 (2007)

Background Reference 03

Mungall, A.J., et al. Nature 425 (6960) :805-811 (2003)

Background Reference 04

Bartolini, F., et al. J. Biol. Chem. 277 (17) :14629-14634 (2002)

Other Product Names

Tubulin-specific chaperone C, Tubulin-folding cofactor C, CFC, TBCC

Tested Applications

WB

Protein ID

313104020

Physical Properties

Liquid

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