SFRS2B Antibody

Product Specifications

Background

The SR (serine/arginine-rich) family contains a number of phosphoproteins that function as essential and alternative splicing factors. The SR family of proteins is characterized by the presence of a ribonucleoprotein (RNP) -type RNA binding motif and a carboxyl-terminal arginine-serine-rich (RS) domain. The protein encoded by this gene is a member of the SR family and functions as an essential splicing factor in vitro. This gene is thought to be an expressed PR264/SC35 retropseudogene.

NCBI Gene ID

10929

Swiss Prot

Q9BRL6

Accession Number

Q9BRL6

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This SFRS2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-73 amino acids from the N-terminal region of human SFRS2B.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

32 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SRSF8

NCBI Official Name

Serine/arginine-rich splicing factor 8

NCBI Organism

Homo sapiens

Background Reference 01

Manley, J.L., et al. Genes Dev. 24 (11) :1073-1074 (2010)

Background Reference 02

Lareau, L.F., et al. Nature 446 (7138) :926-929 (2007)

Background Reference 03

Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

Background Reference 04

Li, J., et al. Mol. Cell. Biol. 23 (21) :7437-7447 (2003)

Other Product Names

Serine/arginine-rich splicing factor 8, Pre-mRNA-splicing factor SRP46, Splicing factor SRp46, Splicing factor, arginine/serine-rich 2B, SRSF8, SFRS2B, SRP46