SLIT1 Antibody
Product Specifications
Background
Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions (By similarity) . SLIT1 and SLIT2 together seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb.
NCBI Gene ID
6585
Swiss Prot
O75093
Accession Number
O75093
Host
Rabbit
Reactivity
Mouse
Immunogen
This SLIT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 84-113 amino acids from the N-terminal region of human SLIT1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=57-020
Calculated Molecular Weight
168 kDa
Fragment
Rabbit Ig
Symbol
SLIT1
NCBI Official Name
Slit homolog 1 protein
NCBI Organism
Homo sapiens
Background Reference 01
Marlow, R., et al. Cancer Res. 68 (19) :7819-7827 (2008)
Background Reference 02
Hussain, S.A., et al. J. Biol. Chem. 281 (51) :39693-39698 (2006)
Background Reference 03
Lin, L., et al. Stem Cells 24 (11) :2504-2513 (2006)
Background Reference 04
Lim, J., et al. Cell 125 (4) :801-814 (2006)
Other Product Names
Slit homolog 1 protein, Slit-1, Multiple epidermal growth factor-like domains protein 4, Multiple EGF-like domains protein 4, SLIT1, KIAA0813, MEGF4, SLIL1
Tested Applications
WB, IHC-P
Physical Properties
Liquid
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