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SLIT1 Antibody

Product Specifications

Background

Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions (By similarity) . SLIT1 and SLIT2 together seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb.

NCBI Gene ID

6585

Swiss Prot

O75093

Accession Number

O75093

Host

Rabbit

Reactivity

Mouse

Immunogen

This SLIT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 84-113 amino acids from the N-terminal region of human SLIT1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

168 kDa

Fragment

Rabbit Ig

Symbol

SLIT1

NCBI Official Name

Slit homolog 1 protein

NCBI Organism

Homo sapiens

Background Reference 01

Marlow, R., et al. Cancer Res. 68 (19) :7819-7827 (2008)

Background Reference 02

Hussain, S.A., et al. J. Biol. Chem. 281 (51) :39693-39698 (2006)

Background Reference 03

Lin, L., et al. Stem Cells 24 (11) :2504-2513 (2006)

Background Reference 04

Lim, J., et al. Cell 125 (4) :801-814 (2006)

Other Product Names

Slit homolog 1 protein, Slit-1, Multiple epidermal growth factor-like domains protein 4, Multiple EGF-like domains protein 4, SLIT1, KIAA0813, MEGF4, SLIL1

Tested Applications

WB, IHC-P

Physical Properties

Liquid

Frequently Asked Questions

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