HtrA1 Antibody

Product Specifications

Background

HtrA1 a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth.

NCBI Gene ID

5654

Swiss Prot

Q92743

Accession Number

Q92743

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This HtrA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-147 amino acids from the N-terminal region of human HtrA1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

51 kDa

Fragment

Rabbit Ig

Symbol

HTRA1

NCBI Official Name

Serine protease HTRA1

NCBI Organism

Homo sapiens

Background Reference 01

Howes, N., et al., Clin Gastroenterol Hepatol 2 (3) :252-261 (2004) .

Background Reference 02

Chien, J., et al., Oncogene 23 (8) :1636-1644 (2004) .

Background Reference 03

Hu, S.I., et al., J. Biol. Chem. 273 (51) :34406-34412 (1998) .

Background Reference 04

Zumbrunn, J., et al., Genomics 45 (2) :461-462 (1997) .

Other Product Names

Serine protease HTRA1, 3421-, High-temperature requirement A serine peptidase 1, L56, Serine protease 11, HTRA1, HTRA, PRSS11

Tested Applications

WB, IHC-P, IF

Protein ID

18202620

Physical Properties

Liquid

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