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WDR45 Antibody

Product Specifications

Background

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene has a pseudogene at chromosome 4q31.3. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity and full-length nature of some variants have not been determined.

NCBI Gene ID

11152

Swiss Prot

Q9Y484

Accession Number

Q9Y484

Host

Rabbit

Reactivity

Human

Immunogen

This WDR45 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-46 amino acids from the N-terminal region of human WDR45.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Zebrafish, Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

40 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

WDR45

NCBI Official Name

WD repeat domain phosphoinositide-interacting protein 4

NCBI Organism

Homo sapiens

Background Reference 01

Proikas-Cezanne, T., et al. Oncogene 23 (58) :9314-9325 (2004)

Background Reference 02

Jeffries, T.R., et al. Mol. Biol. Cell 15 (6) :2652-2663 (2004)

Background Reference 03

Clark, A.G., et al. Science 302 (5652) :1960-1963 (2003)

Other Product Names

WD repeat domain phosphoinositide-interacting protein 4, WIPI-4, WD repeat-containing protein 45, WDR45, WDRX1, WDRXI4, WIPI4

Tested Applications

WB

Protein ID

74762056

Physical Properties

Liquid

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