GFRA4 Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI) -linked cell surface receptor for persephin, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for RET-associated diseases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
NCBI Gene ID
64096
Swiss Prot
Q9GZZ7
Accession Number
Q9GZZ7
Host
Rabbit
Reactivity
Human
Immunogen
This GFRA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-184 amino acids from the Central region of human GFRA4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
32 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
GFRA4
NCBI Official Name
GDNF family receptor alpha-4
NCBI Organism
Homo sapiens
Background Reference 01
Yang, J., et al. FEBS Lett. 569 (1-3), 267-271 (2004) :
Background Reference 02
Borrego, S., et al. J. Med. Genet. 40 (3), E18 (2003) :
Background Reference 03
Deloukas, P., et al. Nature 414 (6866) :865-871 (2001)
Background Reference 04
Zhou, B., et al. Pediatr. Neurol. 25 (2) :156-161 (2001)
Other Product Names
GDNF family receptor alpha-4, GDNF receptor alpha-4, GDNFR-alpha-4, GFR-alpha-4, Persephin receptor, GFRA4
Tested Applications
WB
Protein ID
30173123
Physical Properties
Liquid
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