GFRA4 Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI) -linked cell surface receptor for persephin, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for RET-associated diseases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

NCBI Gene ID

64096

Swiss Prot

Q9GZZ7

Accession Number

Q9GZZ7

Host

Rabbit

Reactivity

Human

Immunogen

This GFRA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-184 amino acids from the Central region of human GFRA4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

32 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

GFRA4

NCBI Official Name

GDNF family receptor alpha-4

NCBI Organism

Homo sapiens

Background Reference 01

Yang, J., et al. FEBS Lett. 569 (1-3), 267-271 (2004) :

Background Reference 02

Borrego, S., et al. J. Med. Genet. 40 (3), E18 (2003) :

Background Reference 03

Deloukas, P., et al. Nature 414 (6866) :865-871 (2001)

Background Reference 04

Zhou, B., et al. Pediatr. Neurol. 25 (2) :156-161 (2001)

Other Product Names

GDNF family receptor alpha-4, GDNF receptor alpha-4, GDNFR-alpha-4, GFR-alpha-4, Persephin receptor, GFRA4

Tested Applications

Protein ID

30173123

Physical Properties

Liquid

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