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DACH2 Antibody

Product Specifications

Background

This gene is one of two genes which encode a protein similar to the Drosophila protein dachshund, a transcription factor involved in cell fate determination in the eye, limb and genital disc of the fly. The encoded protein contains two characteristic dachshund domains: an N-terminal domain responsible for DNA binding and a C-terminal domain responsible for protein-protein interactions. This gene is located on the X chromosome and is subject to inactivation by DNA methylation. The encoded protein may be involved in regulation of organogenesis and myogenesis, and may play a role in premature ovarian failure. Multiple transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

117154

Swiss Prot

Q96NX9

Accession Number

Q96NX9

Host

Rabbit

Reactivity

Human

Immunogen

This DACH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-173 amino acids from the N-terminal region of human DACH2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=56-944

Calculated Molecular Weight

65 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

DACH2

NCBI Official Name

Dachshund homolog 2

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care (2010) In press :

Background Reference 02

Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)

Background Reference 03

Styrkarsdottir, U., et al. Nat. Genet. 41 (1) :15-17 (2009)

Background Reference 04

Poulin, F., et al. Genomics 85 (6) :774-781 (2005)

Other Product Names

Dachshund homolog 2, Dach2, DACH2

Tested Applications

WB

Protein ID

44887818

Physical Properties

Liquid

Curated Selection

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