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SC65 Antibody

Product Specifications

Background

This nucleolar protein was first characterized because it was an autoantigen in cases on interstitial cystitis. The protein, with a predicted molecular weight of 50 kDa, appears to be localized in the particulate compartment of the interphase nucleolus, with a distribution distinct from that of nucleolar protein B23. During mitosis it is associated with chromosomes.

NCBI Gene ID

10609

Swiss Prot

Q92791

Accession Number

Q92791

Host

Rabbit

Reactivity

Human

Immunogen

This SC65 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 361-390 amino acids from the C-terminal region of human SC65.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

50 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

LEPREL4

NCBI Official Name

Synaptonemal complex protein SC65

NCBI Organism

Homo sapiens

Background Reference 01

Foster, L.J., et al. J. Proteome Res. 5 (1) :64-75 (2006)

Background Reference 02

Fossa, A., et al. Br. J. Cancer 83 (6) :743-749 (2000)

Background Reference 03

Ochs, R.L., et al. Mol. Biol. Cell 7 (7) :1015-1024 (1996)

Other Product Names

Synaptonemal complex protein SC65, Leprecan-like protein 4, Nucleolar autoantigen No55, LEPREL4, NOL55, SC65

Tested Applications

WB

Protein ID

3183090

Physical Properties

Liquid

Frequently Asked Questions

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