SGPP1 Antibody

Product Specifications

Background

Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite that regulates diverse biologic processes. SGPP1 catalyzes the degradation of S1P via salvage and recycling of sphingosine into long-chain ceramides (Mandala et al., 2000 [PubMed 10859351]; Le Stunff et al., 2007 [PubMed 17895250]) .[supplied by OMIM].

NCBI Gene ID

81537

Swiss Prot

Q9BX95

Accession Number

Q9BX95

Host

Rabbit

Reactivity

Human

Immunogen

This SGPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-42 amino acids from the N-terminal region of human SGPP1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

49 kDa

Fragment

Rabbit Ig

Symbol

SGPP1

NCBI Official Name

Sphingosine-1-phosphate phosphatase 1

NCBI Organism

Homo sapiens

Background Reference 01

Hicks, A.A., et al. PLoS Genet. (10), E1000672 (2009) :

Background Reference 02

Le Stunff, H., et al. J. Biol. Chem. 282 (47) :34372-34380 (2007)

Background Reference 03

Sugiyama, N., et al. Mol. Cell Proteomics 6 (6) :1103-1109 (2007)

Background Reference 04

Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

Other Product Names

Sphingosine-1-phosphate phosphatase 1, SPPase1, Spp1, hSPP1, hSPPase1, 313-, Sphingosine-1-phosphatase 1, SGPP1

Tested Applications

WB, IHC-P

Protein ID

46577706

Physical Properties

Liquid

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