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WNT16 Antibody

Product Specifications

Background

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It contains two transcript variants diverging at the 5' termini. These two variants are proposed to be the products of separate promoters and not to be splice variants from a single promoter. They are differentially expressed in normal tissues, one of which (variant 2) is expressed at significant levels only in the pancreas, whereas another one (variant 1) is expressed more ubiquitously with highest levels in adult kidney, placenta, brain, heart, and spleen.

NCBI Gene ID

51384

Swiss Prot

Q9UBV4

Accession Number

Q9UBV4

Host

Rabbit

Reactivity

Human

Immunogen

This WNT16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 236-265 amino acids from the C-terminal region of human WNT16.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

41 kDa

Fragment

Rabbit Ig

Symbol

WNT16

NCBI Official Name

Protein Wnt-16

NCBI Organism

Homo sapiens

Background Reference 01

Binet, R., et al. Cancer Res. 69 (24) :9183-9191 (2009)

Background Reference 02

Memarian, A., et al. Leuk. Lymphoma 50 (12) :2061-2070 (2009)

Background Reference 03

Nygren, M.K., et al. Exp. Hematol. 37 (2) :225-233 (2009)

Background Reference 04

Teh, M.T., et al. J. Cell. Sci. 120 (PT 2), 330-339 (2007) :

Other Product Names

Protein Wnt-16, WNT16

Tested Applications

WB, IHC-P

Protein ID

12643875

Physical Properties

Liquid

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