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AFG3L2 Antibody

Product Specifications

Background

This gene encodes a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. This gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders.

NCBI Gene ID

10939

Swiss Prot

Q9Y4W6

Accession Number

Q9Y4W6

Host

Rabbit

Reactivity

Human

Immunogen

This AFG3L2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-80 amino acids from the N-terminal region of human AFG3L2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Obesity, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

89 kDa

Fragment

Rabbit Ig

Symbol

AFG3L2

NCBI Official Name

AFG3-like protein 2

NCBI Organism

Homo sapiens

Background Reference 01

Edener, U., et al. Eur. J. Hum. Genet. 18 (8) :965-968 (2010)

Background Reference 02

Di Bella, D., et al. Nat. Genet. 42 (4) :313-321 (2010)

Background Reference 03

Augustin, S., et al. Mol. Cell 35 (5) :574-585 (2009)

Background Reference 04

Mariotti, C., et al. Cerebellum 7 (2) :184-188 (2008)

Other Product Names

AFG3-like protein 2, 3424-, Paraplegin-like protein, AFG3L2

Tested Applications

WB, IHC-P

Protein ID

126302516

Physical Properties

Liquid

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