NFATC4 Antibody

The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family of nuclear factors of activated T cells also participate in the formation of this complex. The product of this gene plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of the IL-2 and IL-4. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq].

This NFATC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 744-773 amino acids from the C-terminal region of human NFATC4.

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010) Al-Daraji, W.I., et al. J. Cutan. Pathol. 37 (9), E21-E36 (2010) Fougere, M., et al. Oncogene 29 (15) :2292-2301 (2010) Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010) Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)