GRHL2 Antibody

Product Specifications

Background

The protein encoded by this gene is a transcription factor that can act as a homodimer or as a heterodimer with either GRHL1 or GRHL3. Defects in this gene are a cause of non-syndromic sensorineural deafness autosomal dominant type 28 (DFNA28) .

NCBI Gene ID

79977

Swiss Prot

Q6ISB3

Accession Number

Q6ISB3

Host

Rabbit

Reactivity

Human

Immunogen

This GRHL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 409-438 amino acids from the Central region of human GRHL2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

71 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

GRHL2

NCBI Official Name

Grainyhead-like protein 2 homolog

NCBI Organism

Homo sapiens

Background Reference 01

Werth, M., et al. Development 137 (22) :3835-3845 (2010)

Background Reference 02

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 03

Kang, X., et al. Oncogene 28 (4) :565-574 (2009)

Background Reference 04

Tanaka, Y., et al. J. Hepatol. 49 (5) :746-757 (2008)

Other Product Names

Grainyhead-like protein 2 homolog, Brother of mammalian grainyhead, Transcription factor CP2-like 3, GRHL2, BOM, TFCP2L3

Tested Applications

Protein ID

74736618

Physical Properties

Liquid

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