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PLS1 Antibody

Product Specifications

Background

Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. The protein encoded by this gene is a third distinct plastin isoform, which is specifically expressed at high levels in the small intestine. Alternatively spliced transcript variants varying in the 5' UTR, but encoding the same protein, have been found for this gene. A pseudogene of this gene is found on chromosome 11.

NCBI Gene ID

5357

Swiss Prot

Q14651

Accession Number

Q14651

Host

Rabbit

Reactivity

Human

Immunogen

This PLS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 550-579 amino acids from the C-terminal region of human PLS1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

70 kDa

Fragment

Rabbit Ig

Symbol

PLS1

NCBI Official Name

Plastin-1

NCBI Organism

Homo sapiens

Background Reference 01

Chafel, M.M., et al. Dev. Dyn. 203 (2) :141-151 (1995)

Background Reference 02

Lin, C.S., et al. Mol. Cell. Biol. 14 (4) :2457-2467 (1994)

Background Reference 03

Shibata, M., et al. J. Leukoc. Biol. 54 (1) :10-16 (1993)

Background Reference 04

Lin, C.S., et al. J. Biol. Chem. 268 (4) :2781-2792 (1993)

Other Product Names

Plastin-1, Intestine-specific plastin, I-plastin, PLS1

Tested Applications

WB, IHC-P

Protein ID

224471848

Physical Properties

Liquid

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