RARRES1 Antibody
Product Specifications
Background
This gene was identified as a retinoid acid (RA) receptor-responsive gene. It encodes a type 1 membrane protein. The expression of this gene is upregulated by tazarotene as well as by retinoic acid receptors. The expression of this gene is found to be downregulated in prostate cancer, which is caused by the methylation of its promoter and CpG island. Alternatively spliced transcript variant encoding distinct isoforms have been observed.
NCBI Gene ID
5918
Swiss Prot
P49788
Accession Number
P49788
Host
Rabbit
Reactivity
Human
Immunogen
This RARRES1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-163 amino acids from the C-terminal region of human RARRES1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
33 kDa
Fragment
Rabbit Ig
Symbol
RARRES1
NCBI Official Name
Retinoic acid receptor responder protein 1
NCBI Organism
Homo sapiens
Background Reference 01
Wheeler, H.E., et al. PLoS Genet. (10), E1000685 (2009) :
Background Reference 02
Kwok, W.K., et al. Cancer Genet. Cytogenet. 194 (1) :58-64 (2009)
Background Reference 03
Ohnishi, S., et al. Cell Prolif. 42 (3) :309-316 (2009)
Background Reference 04
Son, M.S., et al. Oncol. Res. 17 (11-12), 571-580 (2009) :
Other Product Names
Retinoic acid receptor responder protein 1, Phorbol ester-induced gene 1 protein, PERG-1, RAR-responsive protein TIG1, Tazarotene-induced gene 1 protein, RARRES1, PEIG1, TIG1
Tested Applications
WB, IHC-P
Protein ID
57014141
Physical Properties
Liquid
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