HEMGN Antibody

Product Specifications

Background

HEMGN regulates the proliferation and differentiation of hematopoietic cells. Overexpression block the TPA-induced megakaryocytic differentiation in the K562 cell model. May also prevent cell apoptosis through the activation of the nuclear factor-kappa B (NF-kB) .

NCBI Gene ID

55363

Swiss Prot

Q9BXL5

Accession Number

Q9BXL5

Host

Rabbit

Reactivity

Human

Immunogen

This HEMGN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 420-449 amino acids from the C-terminal region of human HEMGN.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

55 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

HEMGN

NCBI Official Name

Hemogen

NCBI Organism

Homo sapiens

Background Reference 01

Ding, Y.L., et al. J. Cell. Biochem. 110 (4) :866-874 (2010)

Background Reference 02

Moreno, L.M., et al. Hum. Mol. Genet. 18 (24) :4879-4896 (2009)

Background Reference 03

Lowe, J.K., et al. PLoS Genet. (2), E1000365 (2009) :

Background Reference 04

Li, C.Y., et al. Biochim. Biophys. Acta 1779 (10) :606-615 (2008)

Other Product Names

Hemogen, Erythroid differentiation-associated gene protein, EDAG-1, Hemopoietic gene protein, Negative differentiation regulator protein, HEMGN, EDAG, NDR