HOOK1 Antibody

Product Specifications

Background

This gene encodes a member of the hook family of coiled-coil proteins, which bind to microtubules and organelles through their N- and C-terminal domains, respectively. The encoded protein localizes to discrete punctuate subcellular structures, and interacts with several members of the Rab GTPase family involved in endocytosis. It is thought to link endocytic membrane trafficking to the microtubule cytoskeleton. Several alternatively spliced transcript variants have been identified, but the full-length nature of some of these variants has not been determined. [provided by RefSeq].

NCBI Gene ID

51361

Swiss Prot

Q9UJC3

Accession Number

Q9UJC3

Host

Rabbit

Reactivity

Human

Immunogen

This HOOK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 402-431 amino acids from the Central region of human HOOK1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

85 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

HOOK1

NCBI Official Name

Protein Hook homolog 1

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 02

Xu, L., et al. Mol. Biol. Cell 19 (12) :5059-5071 (2008)

Background Reference 03

Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :

Background Reference 04

Beausoleil, S.A., et al. Nat. Biotechnol. 24 (10) :1285-1292 (2006)

Other Product Names

Protein Hook homolog 1, h-hook1, hHK1, HOOK1

Tested Applications

Protein ID

41688595

Physical Properties

Liquid

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