PFDN5 Antibody

Product Specifications

Background

This gene encodes a member of the prefoldin alpha subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. The encoded protein may also repress the transcriptional activity of the proto-oncogene c-Myc. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq].

NCBI Gene ID

5204

Swiss Prot

Q99471

Accession Number

Q99471

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This PFDN5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-108 amino acids from the Central region of human PFDN5.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

17 kDa

Fragment

Rabbit Ig

Symbol

PFDN5

NCBI Official Name

Prefoldin subunit 5

NCBI Organism

Homo sapiens

Background Reference 01

Ma, H.C., et al. J. Biomed. Sci. 15 (4) :417-425 (2008)

Background Reference 02

Yoshida, T., et al. Exp. Cell Res. 314 (6) :1217-1228 (2008)

Background Reference 03

Lubyova, B., et al. J. Biol. Chem. 282 (44) :31944-31953 (2007)

Background Reference 04

Hagio, Y., et al. J. Cell. Biochem. 97 (1) :145-155 (2006)

Other Product Names

Prefoldin subunit 5, C-Myc-binding protein Mm-1, Myc modulator 1, PFDN5, MM1, PFD5

Tested Applications

WB, IHC-P

Protein ID

12231038

Physical Properties

Liquid

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