SP2 Antibody
Product Specifications
Background
This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein contains the least conserved DNA-binding domain within the Sp subfamily of proteins, and its DNA sequence specificity differs from the other Sp proteins. It localizes primarily within subnuclear foci associated with the nuclear matrix, and can activate or in some cases repress expression from different promoters.
NCBI Gene ID
6668
Swiss Prot
Q02086
Accession Number
Q02086
Host
Rabbit
Reactivity
Mouse
Immunogen
This SP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 498-526 amino acids from the C-terminal region of human SP2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
65 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SP2
NCBI Official Name
Transcription factor Sp2
NCBI Organism
Homo sapiens
Background Reference 01
Ito, H., et al. Biochim. Biophys. Acta 1789 (11-12), 681-690 (2009) :
Background Reference 02
Wheeler, H.E., et al. PLoS Genet. (10), E1000685 (2009) :
Background Reference 03
Letourneur, M., et al. Mol. Immunol. 46 (11-12), 2151-2160 (2009) :
Background Reference 04
Sun, J.M., et al. J. Biol. Chem. 282 (45) :33227-33236 (2007)
Other Product Names
Transcription factor Sp2, SP2, KIAA0048
Tested Applications
WB
Protein ID
119370531
Physical Properties
Liquid
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