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SP2 Antibody

Product Specifications

Background

This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein contains the least conserved DNA-binding domain within the Sp subfamily of proteins, and its DNA sequence specificity differs from the other Sp proteins. It localizes primarily within subnuclear foci associated with the nuclear matrix, and can activate or in some cases repress expression from different promoters.

NCBI Gene ID

6668

Swiss Prot

Q02086

Accession Number

Q02086

Host

Rabbit

Reactivity

Mouse

Immunogen

This SP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 498-526 amino acids from the C-terminal region of human SP2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=56-861

Calculated Molecular Weight

65 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SP2

NCBI Official Name

Transcription factor Sp2

NCBI Organism

Homo sapiens

Background Reference 01

Ito, H., et al. Biochim. Biophys. Acta 1789 (11-12), 681-690 (2009) :

Background Reference 02

Wheeler, H.E., et al. PLoS Genet. (10), E1000685 (2009) :

Background Reference 03

Letourneur, M., et al. Mol. Immunol. 46 (11-12), 2151-2160 (2009) :

Background Reference 04

Sun, J.M., et al. J. Biol. Chem. 282 (45) :33227-33236 (2007)

Other Product Names

Transcription factor Sp2, SP2, KIAA0048

Tested Applications

WB

Protein ID

119370531

Physical Properties

Liquid

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