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MEPCE Antibody

Product Specifications

Background

S-adenosyl-L-methionine-dependent methyltransferase that adds a methylphosphate cap at the 5'-end of 7SK snRNA, leading to stabilize it.

NCBI Gene ID

56257

Swiss Prot

Q7L2J0

Accession Number

Q7L2J0

Host

Rabbit

Reactivity

Mouse

Immunogen

This MEPCE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-267 amino acids from the Central region of human MEPCE.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

74 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

MEPCE

NCBI Official Name

7SK snRNA methylphosphate capping enzyme

NCBI Organism

Homo sapiens

Background Reference 01

Xue, Y., et al. Nucleic Acids Res. 38 (2) :360-369 (2010)

Background Reference 02

Krueger, B.J., et al. Nucleic Acids Res. 36 (7) :2219-2229 (2008)

Background Reference 03

Kaneko, S., et al. Proc. Natl. Acad. Sci. U.S.A. 104 (45) :17620-17625 (2007)

Background Reference 04

Jeronimo, C., et al. Mol. Cell 27 (2) :262-274 (2007)

Other Product Names

7SK snRNA methylphosphate capping enzyme, MePCE, 211-, Bicoid-interacting protein 3 homolog, Bin3 homolog, MEPCE, BCDIN3

Tested Applications

WB

Protein ID

74758999

Physical Properties

Liquid

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