KAT2A Antibody
Product Specifications
Background
KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]) .
NCBI Gene ID
2648
Swiss Prot
Q92830
Accession Number
Q92830
Host
Rabbit
Reactivity
Human
Immunogen
This KAT2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 611-638 amino acids from the C-terminal region of human KAT2A.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
94 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
KAT2A
NCBI Official Name
Histone acetyltransferase KAT2A
NCBI Organism
Homo sapiens
Background Reference 01
Terreni, M., et al. Retrovirology 7, 18 (2010) :
Background Reference 02
Atanassov, B.S., et al. Mol. Cell 35 (3) :352-364 (2009)
Background Reference 03
Kelly, T.J., et al. J. Biol. Chem. 284 (30) :19945-19952 (2009)
Background Reference 04
Mao, X., et al. Genes Dev. 23 (7) :849-861 (2009)
Other Product Names
Histone acetyltransferase KAT2A, General control of amino acid synthesis protein 5-like 2, Histone acetyltransferase GCN5, HsGCN5, Lysine acetyltransferase 2A, STAF97, KAT2A, GCN5, GCN5L2, HGCN5
Tested Applications
WB
Protein ID
209572743
Physical Properties
Liquid
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