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KCNV2 Antibody

Product Specifications

Background

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium voltage-gated channel subfamily V. This member is identified as a 'silent subunit', and it does not form homomultimers, but forms heteromultimers with several other subfamily members. Through obligatory heteromerization, it exerts a function-altering effect on other potassium channel subunits. This protein is strongly expressed in pancreas and has a weaker expression in several other tissues.

NCBI Gene ID

169522

Swiss Prot

Q8TDN2

Accession Number

Q8TDN2

Host

Rabbit

Reactivity

Human

Immunogen

This KCNV2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 478-507 amino acids from the C-terminal region of human KCNV2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=56-841

Calculated Molecular Weight

62 kDa

Fragment

Rabbit Ig

Symbol

KCNV2

NCBI Official Name

Potassium voltage-gated channel subfamily V member 2

NCBI Organism

Homo sapiens

Background Reference 01

Robson, A.G., et al. Retina (Philadelphia, Pa.) 30 (1) :51-62 (2010)

Background Reference 02

Ben Salah, S., et al. Am. J. Ophthalmol. 145 (6) :1099-1106 (2008)

Background Reference 03

Wissinger, B., et al. Invest. Ophthalmol. Vis. Sci. 49 (2) :751-757 (2008)

Background Reference 04

Thiagalingam, S., et al. Ophthalmic Genet. 28 (3) :135-142 (2007)

Other Product Names

Potassium voltage-gated channel subfamily V member 2, Voltage-gated potassium channel subunit Kv82, KCNV2

Tested Applications

WB, IHC-P

Protein ID

26006804

Physical Properties

Liquid

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