WDR12 Antibody

Product Specifications

Background

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein is highly similar to the mouse WD repeat domain 12 protein at the amino acid level. The protein encoded by this gene is a component of a nucleolar protein complex that affects maturation of the large ribosomal subunit.

NCBI Gene ID

55759

Swiss Prot

Q9GZL7

Accession Number

Q9GZL7

Host

Rabbit

Reactivity

Human

Immunogen

This WDR12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-239 amino acids from the Central region of human WDR12.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

48 kDa

Fragment

Rabbit Ig

Symbol

WDR12

NCBI Official Name

Ribosome biogenesis protein WDR12 {ECO:0000255|HAMAP-Rule:MF_03029}

NCBI Organism

Homo sapiens

Background Reference 01

Kathiresan, S., et al. Nat. Genet. 41 (3) :334-341 (2009)

Background Reference 02

Rohrmoser, M., et al. Mol. Cell. Biol. 27 (10) :3682-3694 (2007)

Background Reference 03

Higa, L.A., et al. Nat. Cell Biol. 8 (11) :1277-1283 (2006)

Background Reference 04

Grimm, T., et al. Nucleic Acids Res. 34 (10) :3030-3043 (2006)

Other Product Names

Ribosome biogenesis protein WDR12 {ECO:0000255|HAMAP-Rule:MF_03029}, WD repeat-containing protein 12 {ECO:0000255|HAMAP-Rule:MF_03029}, WDR12 {ECO:0000255|HAMAP-Rule:MF_03029}