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GNLY Antibody

Product Specifications

Background

The product of this gene is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. This protein is present in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms. Alternatively spliced transcript variants encoding different isoforms have been identified.

NCBI Gene ID

10578

Swiss Prot

P22749

Accession Number

P22749

Host

Rabbit

Reactivity

Human

Immunogen

This GNLY antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-42 amino acids from the N-terminal region of human GNLY.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

16 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

GNLY

NCBI Official Name

Granulysin

NCBI Organism

Homo sapiens

Background Reference 01

Xing, J., et al. J. Immunol. 185 (9) :5074-5081 (2010)

Background Reference 02

Schuurhof, A., et al. Pediatr. Pulmonol. 45 (6) :608-613 (2010)

Background Reference 03

Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)

Background Reference 04

Yang, C., et al. Int. J. Tuberc. Lung Dis. 13 (11) :1360-1366 (2009)

Other Product Names

Granulysin, Lymphokine LAG-2, Protein NKG5, T-cell activation protein 519, GNLY, LAG2, NKG5, TLA519

Tested Applications

WB

Protein ID

116242500

Physical Properties

Liquid

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