LNX2 Antibody
Product Specifications
Background
LNX2 (Ligand of numb-protein X 2) is a multimodular protein that binds to NUMB via the NPXY motif. It may serve as a molecular scaffold that localizes unrelated, interacting proteins, such as NUMB, to specific subcellular sites.
NCBI Gene ID
222484
Swiss Prot
Q8N448
Accession Number
Q8N448
Host
Rabbit
Reactivity
Human
Immunogen
This LNX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 551-579 amino acids from the C-terminal region of human LNX2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
76 kDa
Fragment
Rabbit Ig
Symbol
LNX2
NCBI Official Name
Ligand of Numb protein X 2
NCBI Organism
Homo sapiens
Background Reference 01
Thorleifsson, G., et al. Nat. Genet. 41 (1) :18-24 (2009)
Background Reference 02
Sullivan, P.F., et al. Mol. Psychiatry 13 (6) :570-584 (2008)
Background Reference 03
Dunham, A., et al. Nature 428 (6982) :522-528 (2004)
Background Reference 04
Rice, D.S., et al. Mol. Cell. Neurosci. 18 (5) :525-540 (2001)
Other Product Names
Ligand of Numb protein X 2, Numb-binding protein 2, PDZ domain-containing RING finger protein 1, LNX2, PDZRN1
Tested Applications
WB, IHC-P
Protein ID
29840784
Physical Properties
Liquid
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