Bcl-w Antibody

Product Specifications

Background

Bcl-w is a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis.

NCBI Gene ID

599

Swiss Prot

Q92843

Accession Number

Q92843

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This Bcl antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-59 amino acids from human Bcl.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

21 kDa

Fragment

Rabbit Ig

Symbol

BCL2L2

NCBI Official Name

Bcl-2-like protein 2

NCBI Organism

Homo sapiens

Background Reference 01

Denisov, A.Y., et al., J. Biol. Chem. 278 (23) :21124-21128 (2003) .

Background Reference 02

Hinds, M.G., et al., EMBO J. 22 (7) :1497-1507 (2003) .

Background Reference 03

Middleton, G., et al., Development 128 (3) :447-457 (2001) .

Background Reference 04

Ross, A.J., et al., Nat. Genet. 18 (3) :251-256 (1998) .

Other Product Names

Bcl-2-like protein 2, Bcl2-L-2, Apoptosis regulator Bcl-W, BCL2L2, BCLW, KIAA0271

Tested Applications

WB, IHC-P

Protein ID

296434404

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

NBP2-72401H 0.1 mL

Mouse Monoclonal C10orf82 Antibody (OTI1G4) [HRP]

Ask

View Details

044812 10 µg

FGF-23, Fc, Recombinant, Human (Fibroblast Growth Factor 23, Tumor-derived Hypophosphatemia-inducing Factor)

Ask

View Details

RC232829 10 µg

AHCYL1 (NM_001242673) Human Tagged ORF Clone

Ask

View Details

FY-ER3869 96 Well

Rat Tcf20 (Transcription factor 20) ELISA Kit

Ask

View Details