CGB/HCG-Beta Antibody

This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG) . Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene.

This CGB/HCG-Beta antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137-165 amino acids from the C-terminal region of human CGB/HCG-Beta.

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cole, L.A. Placenta 31 (8) :653-664 (2010) Ra, Y.J., et al. Interact Cardiovasc Thorac Surg 11 (1) :114-116 (2010) Verma, B., et al. J. Immunol. 184 (4) :2156-2165 (2010) Handschuh, K., et al. Placenta 30 (12) :1016-1022 (2009) Reisenbichler, E.S., et al. Breast15 (5) :527-530 (2009)