HERV-FRD Antibody
Product Specifications
Background
Human endogenous retroviruses (HERVs) make up approximately 8% of the human genome. Although most HERVs are nonfunctional, the HERV-W (ERVWE1; MIM 604659) and HERV-FRD envelope (env) proteins can induce cell-cell fusion when expressed in cells possessing appropriate receptors (Blaise et al., 2003 [PubMed 14557543]) .
NCBI Gene ID
405754
Swiss Prot
P60508
Accession Number
P60508
Host
Rabbit
Reactivity
Human
Immunogen
This HERV-FRD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-107 amino acids from the N-terminal region of human HERV-FRD.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Monkey
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
60 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
ERVFRD-1
NCBI Official Name
Syncytin-2
NCBI Organism
Homo sapiens
Background Reference 01
Vargas, A., et al. J. Mol. Biol. 392 (2) :301-318 (2009)
Background Reference 02
Chen, C.P., et al. Biol. Reprod. 79 (5) :815-823 (2008)
Background Reference 03
Malassine, A., et al. Retrovirology 5, (2008) :
Background Reference 04
Mangeney, M., et al. Proc. Natl. Acad. Sci. U.S.A. 104 (51) :20534-20539 (2007)
Other Product Names
Syncytin-2, Endogenous retrovirus group FRD member 1, Envelope polyprotein, HERV-FRD, HERV-FRD_6p241 provirus ancestral Env polyprotein, Surface protein, SU, Transmembrane protein, TM, ERVFRD-1, ERVFRDE1
Tested Applications
WB
Protein ID
44887864
Physical Properties
Liquid
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