PIGV Antibody

Product Specifications

Background

Glycosylphosphatidylinositol (GPI) is a complex glycolipid that anchors many proteins to the cell surface. The biosynthetic pathway of GPI is mediated by sequential addition of sugars and other components to phosphatidylinositol. PIGV adds the second mannose to the GPI core (Kang et al., 2005 [PubMed 15623507]) .

NCBI Gene ID

55650

Swiss Prot

Q9NUD9

Accession Number

Q9NUD9

Host

Rabbit

Reactivity

Human

Immunogen

This PIGV antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 343-371 amino acids from the C-terminal region of human PIGV.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

56 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PIGV

NCBI Official Name

GPI mannosyltransferase 2

NCBI Organism

Homo sapiens

Background Reference 01

Krawitz, P.M., et al. Nat. Genet. 42 (10) :827-829 (2010)

Background Reference 02

Kang, J.Y., et al. J. Biol. Chem. 280 (10) :9489-9497 (2005)

Background Reference 03

Fabre, A.L., et al. FEBS J. 272 (5) :1160-1168 (2005)

Background Reference 04

Kinoshita, T., et al. Curr Opin Chem Biol 4 (6) :632-638 (2000)

Other Product Names

GPI mannosyltransferase 2, 241-, GPI mannosyltransferase II, GPI-MT-II, Phosphatidylinositol-glycan biosynthesis class V protein, PIG-V, PIGV

Tested Applications

Protein ID

74752975

Physical Properties

Liquid

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