GIF Antibody

Product Specifications

Background

This gene is a member of the cobalamin transport protein family. It encodes a glycoprotein secreted by parietal cells of the gastric mucosa and is required for adequate absorption of vitamin B12. Vitamin B12 is necessary for erythrocyte maturation and mutations in this gene may lead to congenital pernicious anemia.

NCBI Gene ID

2694

Swiss Prot

P27352

Accession Number

P27352

Host

Rabbit

Reactivity

Human

Immunogen

This GIF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 189-218 amino acids from the Central region of human GIF.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

45 kDa

Fragment

Rabbit Ig

Symbol

GIF

NCBI Official Name

Gastric intrinsic factor

NCBI Organism

Homo sapiens

Background Reference 01

Levine, A.J., et al. Cancer Epidemiol. Biomarkers Prev. 19 (7) :1812-1821 (2010)

Background Reference 02

Andersen, C.B., et al. Nature 464 (7287) :445-448 (2010)

Background Reference 03

Ament, A.E., et al. Br. J. Haematol. 144 (4) :622-624 (2009)

Background Reference 04

Remacha, A.F., et al. Ann. Hematol. 87 (7) :599-600 (2008)

Other Product Names

Gastric intrinsic factor, Intrinsic factor, IF, INF, GIF, IFMH

Tested Applications

WB, IHC-P, IF, Flow

Protein ID

62906845

Physical Properties

Liquid

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