FPR3 Antibody

Product Specifications

Background

Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.

NCBI Gene ID

2359

Swiss Prot

P25089

Accession Number

P25089

Host

Rabbit

Reactivity

Human

Immunogen

This FPR3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-351 amino acids from the C-terminal region of human FPR3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction, Growth Factors

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

40 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

FPR3

NCBI Official Name

N-formyl peptide receptor 3

NCBI Organism

Homo sapiens

Background Reference 01

Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)

Background Reference 02

Kim, S.D., et al. J. Immunol. 183 (9) :5511-5517 (2009)

Background Reference 03

Devosse, T., et al. J. Immunol. 182 (8) :4974-4984 (2009)

Background Reference 04

Lambert, N.A. Sci Signal (25), RE5 (2008) :

Other Product Names

N-formyl peptide receptor 3, FMLP-related receptor II, FMLP-R-II, Formyl peptide receptor-like 2, FPR3, FPRH1, FPRL2

Tested Applications

Protein ID

38258904

Physical Properties

Liquid

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