UQCRB Antibody

Product Specifications

Background

This gene encodes a protein which is part of the ubiquinol-cytochrome c oxidoreductase complex which contains ten nuclear-encoded and one mitochondrial-encoded subunits. The encoded protein binds ubiquinone and participates in the transfer of electrons when ubiquinone is bound. Mutations in this gene are associated with mitochondrial complex III deficiency. A pseudogene has been described on the X chromosome.

NCBI Gene ID

7381

Swiss Prot

P14927

Accession Number

P14927

Host

Rabbit

Reactivity

Mouse

Immunogen

This UQCRB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 34-61 amino acids from the Central region of human UQCRB.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

14 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

UQCRB

NCBI Official Name

Cytochrome b-c1 complex subunit 7

NCBI Organism

Homo sapiens

Background Reference 01

Wang, L., et al. Cancer Epidemiol. Biomarkers Prev. 17 (12) :3558-3566 (2008)

Background Reference 02

Haut, S., et al. Hum. Genet. 113 (2) :118-122 (2003)

Background Reference 03

Malaney, S., et al. Cytogenet. Cell Genet. 73 (4) :297-299 (1996)

Background Reference 04

Suzuki, H., et al. J. Biol. Chem. 265 (14) :8159-8163 (1990)

Other Product Names

Cytochrome b-c1 complex subunit 7, Complex III subunit 7, Complex III subunit VII, QP-C, Ubiquinol-cytochrome c reductase complex 14 kDa protein, UQCRB, UQBP