TLE4 Antibody

Product Specifications

Background

TLE4 is a transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity) .

NCBI Gene ID

7091

Swiss Prot

Q04727

Accession Number

Q04727

Host

Rabbit

Reactivity

Human

Immunogen

This TLE4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 167-196 amino acids from the N-terminal region of human TLE4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

84 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

TLE4

NCBI Official Name

Transducin-like enhancer protein 4

NCBI Organism

Homo sapiens

Background Reference 01

Liu, Y., et al. PLoS Genet. (11), E1000707 (2009) :

Background Reference 02

Hancock, D.B., et al. PLoS Genet. (8), E1000623 (2009) :

Background Reference 03

Stolk, L., et al. Nat. Genet. (2009) In press :

Background Reference 04

Dayyani, F., et al. Blood 111 (8) :4338-4347 (2008)

Other Product Names

Transducin-like enhancer protein 4, Grg-4, Groucho-related protein 4, TLE4, GRG4, KIAA1261

Tested Applications

Protein ID

158518541

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

E28PB2001 100 µL

FCRL3 Rabbit Polyclonal Antibody (C-term)

Ask

View Details

441356 51ml

Amineptine (1.0mg/ml in Methanol) discontinued

Ask

View Details

RDM-CSB-02 500 g

Corn Starch Medium

Ask

View Details

RC206802L4 10 µg

mLN64 (STARD3) (NM_006804) Human Tagged Lenti ORF Clone

Ask

View Details

GTR15087078 1 Vial

Lentiviral human FOXR1 shRNA (UAS) - Lentiviral human FOXR1 shRNA (UAS) (100)

Ask

View Details

A26754-100UL 100 µL

KCNJ1 Antibody

Ask

View Details