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RAB11B Antibody

Product Specifications

Background

The Ras superfamily of small GTP-binding proteins, which includes the Ras (see MIM 190020), Ral (see MIM 179550), Rho (see MIM 165390), Rap (see MIM 179520), and Rab (see MIM 179508) families, is involved in controlling a diverse set of essential cellular functions. The Rab family, including RAB11B, appears to play a critical role in regulating exocytotic and endocytotic pathways (summary by Zhu et al., 1994 [PubMed 7811277]) .[supplied by OMIM].

NCBI Gene ID

9230

Swiss Prot

Q15907

Accession Number

Q15907

Host

Rabbit

Reactivity

Human, Rat

Immunogen

This RAB11B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 164-193 amino acids from the C-terminal region of human RAB11B.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

24 kDa

Fragment

Rabbit Ig

Symbol

RAB11B

NCBI Official Name

Ras-related protein Rab-11B

NCBI Organism

Homo sapiens

Background Reference 01

Agop-Nersesian, C., et al. PLoS Pathog. (7), E1001029 (2010) :

Background Reference 02

Silvis, M.R., et al. Mol. Biol. Cell 20 (8) :2337-2350 (2009)

Background Reference 03

Kathiresan, S., et al. Nat. Genet. 41 (1) :56-65 (2009)

Background Reference 04

Scapin, S.M., et al. J. Struct. Biol. 154 (3) :260-268 (2006)

Other Product Names

Ras-related protein Rab-11B, GTP-binding protein YPT3, RAB11B, YPT3

Tested Applications

WB, IHC-P

Protein ID

38258938

Physical Properties

Liquid

Curated Selection

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