PKP2 Antibody
Product Specifications
Background
This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This gene product may regulate the signaling activity of beta-catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high similarity to this locus has been mapped to chromosome 12p13.
NCBI Gene ID
5318
Swiss Prot
Q99959
Accession Number
Q99959
Host
Rabbit
Reactivity
Human
Immunogen
This PKP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 838-866 amino acids from the C-terminal region of human PKP2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
97 kDa
Fragment
Rabbit Ig
Symbol
PKP2
NCBI Official Name
Plakophilin-2
NCBI Organism
Homo sapiens
Background Reference 01
Fressart, V., et al. Europace 12 (6) :861-868 (2010)
Background Reference 02
Cox, M.G., et al. Circ Arrhythm Electrophysiol 3 (2) :126-133 (2010)
Background Reference 03
Christensen, A.H., et al. Cardiology 115 (2) :148-154 (2010)
Background Reference 04
Den Haan, A.D., et al. Circ Cardiovasc Genet 2 (5) :428-435 (2009)
Other Product Names
Plakophilin-2, PKP2
Tested Applications
WB, IHC-P
Protein ID
296452867
Physical Properties
Liquid
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Rabbit Polyclonal GPRASP2 Antibody [Alexa Fluor 405]](https://cdn.genprice.uk/genprice/uk/genprice2.webp)
B2050-01H-ML750 100 µL
BIRC3, NT (Baculoviral IAP Repeat-containing Protein 3, Apoptosis Inhibitor 2, API2, C-IAP2, IAP Homolog C, Inhibitor of Apoptosis Protein 1, IAP-1, hIAP-1, hIAP1, RING Finger Protein 49, TNFR2-TRAF-signaling Complex Protein 1, API2, IAP1, MIHC, RNF49) (MaxLight 750) discontinued
Ask
View Details