D SUMO Antibody
Product Specifications
Background
Covalent modification of target lysines by SUMO (small ubiquitin-like modifier) modulates processes such as protein localization, transcription, nuclear transport, mitosis, DNA replication and repair, signal transduction, and viral reproduction. SUMO does not seem to be involved in protein degradation and may in fact function as an antagonist of ubiquitin in the degradation process. In the development of Drosophila, SUMO plays a maternal role in anterior-posterior (A/P) polarity and patterning.
NCBI Gene ID
33981
Swiss Prot
O97102
Accession Number
O97102
Host
Rabbit
Reactivity
Human, Drosophila
Immunogen
This Drosophila SUMO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-66 amino acids from the C-terminal region of human Drosophila SUMO.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
10 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
O97102
NCBI Official Name
CG4494-PA
NCBI Organism
Drosophila melanogaster
Background Reference 01
Muller S, et al., Nat Rev Mol Cell Biol. 2001 2 (3) :202-10 Review.
Background Reference 02
Hochstrasser M. Cell. 2001 107 (1) :5-8. Review.
Background Reference 03
Kahyo T, et al., Mol Cell. 2001 Sep;8 (3) :713-8.
Background Reference 04
Yeh ET, et al., Gene. 2000 May 2;248 (1-2) :1-14. Review.
Other Product Names
CG4494-PA; LD07775p; Smt3; Ubiquitin-like protein SMT3
Tested Applications
WB
Physical Properties
Liquid
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