ZFP91 Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the zinc finger family of proteins. The gene product contains C2H2-type domains, which are the classical zinc finger domains found in numerous nucleic acid-binding proteins. This protein functions as a regulator of the non-canonical NF-kappaB pathway in lymphotoxin-beta receptor signaling. Alternative splicing results in multiple transcript variants. A read-through transcript variant composed of ZFP91 and the downstream CNTF gene sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse. A ZFP91-related pseudogene has also been identified on chromosome 2.

NCBI Gene ID

80829

Swiss Prot

Q96JP5

Accession Number

Q96JP5

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This ZFP91 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 216-245 amino acids from the Central region of human ZFP91.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

63 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:2000

Symbol

ZFP91

NCBI Official Name

E3 ubiquitin-protein ligase ZFP91

NCBI Organism

Homo sapiens

Background Reference 01

Jin, H.R., et al. Biochem. Biophys. Res. Commun. 400 (4) :581-586 (2010)

Background Reference 02

Jin, X., et al. J. Biol. Chem. 285 (40) :30539-30547 (2010)

Background Reference 03

Kiem, H.P., et al. Exp. Hematol. 38 (9) :819-822 (2010)

Background Reference 04

Sugiyama, N., et al. Mol. Cell Proteomics 6 (6) :1103-1109 (2007)

Other Product Names

E3 ubiquitin-protein ligase ZFP91, 632-, Zinc finger protein 757, Zinc finger protein 91 homolog, Zfp-91, ZFP91, ZNF757

Tested Applications

Protein ID

60416377

Physical Properties

Liquid

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