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SP140 Antibody

Product Specifications

Background

Component of the nuclear body, also known as nuclear domain 10, PML oncogenic domain, and KR body. May be involved in the pathogenesis of acute promyelocytic leukemia and viral infection.

NCBI Gene ID

11262

Swiss Prot

Q13342

Accession Number

Q13342

Host

Rabbit

Reactivity

Human

Immunogen

This SP140 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 272-301 amino acids from the Central region of human SP140.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=56-709

Calculated Molecular Weight

98 kDa

Fragment

Rabbit Ig

Symbol

SP140

NCBI Official Name

Nuclear body protein SP140 {ECO:0000312|HGNC:HGNC:17133}

NCBI Organism

Homo sapiens

Background Reference 01

Slager, S.L., et al. Cancer Epidemiol. Biomarkers Prev. 19 (4) :1098-1102 (2010)

Background Reference 02

Di Bernardo, M.C., et al. Nat. Genet. 40 (10) :1204-1210 (2008)

Background Reference 03

Madani, N., et al. J. Virol. 76 (21) :11133-11138 (2002)

Background Reference 04

Bloch, D.B., et al. J. Biol. Chem. 271 (46) :29198-29204 (1996)

Other Product Names

HGNC:17133

Tested Applications

WB, IHC-P, IF

Protein ID

218511671

Physical Properties

Liquid

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