PIK3AP1 Antibody
Product Specifications
Background
PIK3AP1 is involved in the activation of phosphoinositide 3-kinase (PI3K) in B-cells and in natural killer (NK) cells. Couples B-cell antigen receptor (BCR) to PI3K activation by providing a docking site for the PI3K subunit PIK3R1, which contributes to B-cell development. Seems to have a complementary role with CD19 in PI3K activation (By similarity) . May be involved in the survival of mature B cells via activation of REL (By similarity) .
NCBI Gene ID
118788
Swiss Prot
Q6ZUJ8
Accession Number
Q6ZUJ8
Host
Rabbit
Reactivity
Human
Immunogen
This PIK3AP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 639-668 amino acids from the C-terminal region of human PIK3AP1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=56-700
Calculated Molecular Weight
90 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PIK3AP1
NCBI Official Name
Phosphoinositide 3-kinase adapter protein 1
NCBI Organism
Homo sapiens
Background Reference 01
Koutros, S., et al. Cancer Res. 70 (6) :2389-2396 (2010)
Background Reference 02
Rikova, K., et al. Cell 131 (6) :1190-1203 (2007)
Background Reference 03
Grupe, A., et al. Am. J. Hum. Genet. 78 (1) :78-88 (2006)
Background Reference 04
Maruoka, M., et al. FEBS Lett. 579 (14) :2986-2990 (2005)
Other Product Names
Phosphoinositide 3-kinase adapter protein 1, B-cell adapter for phosphoinositide 3-kinase, B-cell phosphoinositide 3-kinase adapter protein 1, PIK3AP1, BCAP
Tested Applications
WB
Protein ID
205830907
Physical Properties
Liquid
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